Biotechnology is, in many ways, in a constant state of transition. New technologies continue to evolve to meet the ongoing need for novel products. The biomanufacturing segment of the industry is also undergoing its own transformation. It’s known as Bioprocess 4.0 and is designed to help manufacture new therapeutics more efficiently, safely, and economically with the goal of optimizing the overall process. Improved analytics, predictive modeling, and advanced automation are some of the techniques driving the new biomanufacturing paradigm.

Sartorius has long been a leader in bioprocessing and its expertise is clearly on display in this e-book, specifically in the company’s adoption of advanced monitoring techniques in bioproduction. Here you will read about how Sartorius uses state-of-the art biosensors to carry out critical monitoring procedures during bioreactor operations. Clean room environments must be kept sterile to ensure the safety of biotech products and Sartorius scientists describe the steps they take to do so. Gene therapy is one of the most rapidly advancing areas of biotherapeutic development and manufacturing these products comes with its own set of technical challenges that Sartorius addresses in another article. Finally, Sartorius details how the company uses an advanced, rapid, real-time PCR-based system to detect potential sources of microbial contamination during biomanufacturing.

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