August 1, 2006 (Vol. 26, No. 14)
Strong Points: Data collection
Weak Points: Unfriendly interface
I don’t think there has been a technique-related topic relevant to eukaryotic biology in recent years that has garnered as much interest as RNA interference or siRNA. Perhaps because these biological phenomena have given hope to everyone wishing to design a way of significantly reducing expression of desired genes at will. The stage is set, therefore, for a database to keep track of these sequences/information, and that is where siRNA Database and RNA Interference Resources enters the picture. With a listing of relevant sequences for humans, mice, rats, and other organisms, as well as hyperlinked references, the site provides essential information for exploiting the technique. Researchers will welcome this information in an easy-to-access format.