Aseptic Production-Scale Lyophilizer

SP Scientific

The LyoConstellation S10, S20, and S30 are part of a new series of advanced freeze dryers. All are configured to order for faster delivery freeze-drying cycle development and small-scale aseptic production, such as the production of stability batches or early phase clinical trial batches. LyoConstellation, a Line of Sight™–enabled freeze-
drying system with powerful refrigeration, can deliver an expanded equipment capability and an extensive process space. This can allow the development of highly aggressive cycles and the mapping of the furthest reaches of theoretical design space for a formulation. The lyophilizers offer a capacity of 9.8 ft2 (1 m2) and precise shelf temperature control from −55 °C to +65 °C. The LyoConstellation S10 is designed, even when fully loaded, to hold 100 mTorr vacuum and shelf temperatures of over +40 °C, enabling high sublimation rates with high-moisture applications with no evidence of choked flow. Isolator and cleanroom integratable, the LyoConstellation is capable of clean-in-place (CIP) and steam-in-place (SIP) functionality for aseptic manufacturing.

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