Biothorpe Pharmaceuticals’ IP includes the use of siRNAs and other oligonucleotides directed at the Syk kinase.

ZaBeCor Pharmaceuticals has formed a subsidiary, Biothorpe Pharmaceuticals, to focus on the development of siRNA, antisense, and other molecular technologies for cancer treatment. Biothorpe’s intellectual property (IP) portfolio includes the therapeutic use of siRNA and other oligonucleotides directed at Syk kinase, which is required for the proliferation of malignant cells in several cancers, according to some studies.

The company intends to license its IP for the treatment of three cancers: acute myelogenous leukemia, B-cell lymphoma, and chronic lymphocytic leukemia. Biothorpe’s IP is based upon research conducted at the University of Pennsylvania School of Medicine.

“ZaBeCor will continue to focus on inflammatory disorders, particularly on developing our anti-inflammatory drug candidate Excellair™, while Biothorpe builds upon the groundbreaking research of applying siRNA technology toward malignant cells in the blood and lymphatic system.”

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