Project will involve 60 institutes and includes a sevenfold increase in DNA samples from last year’s WTCC.

The Wellcome Trust is bankrolling another huge genetic investigation with £30 million, or $59.96 million. The backing is more than three times that of last year’s Wellcome Trust Case Control Consortium (WTCC) of £9 million.

Planned as a follow-up to the WTCC, the new genome-wide association studies will bring together researchers from at least 60 institutions who will investigate 25 diseases, individuals’ responses to statins, as well as learning in children.
DNA samples from 120,000 people will be analyzed representing a sevenfold increase in the number of samples. Scientitsts will examine between 500,000 and 1 million SNPs per sample as well as a comprehensive set of copy number variants.

The Wellcome Trust Sanger Institute will devote a large part of its high-throughput genotyping pipeline. Most of the data analysis will be undertaken at the Wellcome Trust Centre for Human Genetics at the University of Oxford.

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