Reproducible Synthetic Hydrogel Scaffold Supports Growth of Pancreatic and Other Tissue Organoids

MIT engineers, working with scientists at Cancer Research UK Manchester Institute, developed a new way to grow pancreatic organoids—tiny replicas of the pancreas—from either healthy or cancerous pancreatic cells. Using a specialized synthetic hydrogel scaffold to mimic the extracellular environment, the researchers generated tiny pancreatic organoid structures that could be used to study the important interactions between pancreatic tumors and their environment.