Microbiome’s Metabolism Altered by Bioaccumulation of Medications

A new study shows that common medications can accumulate in gut bacteria, altering bacterial function and potentially reducing the effectiveness of the drug. This bioaccumulation by gut bacteria may have implications for microbiota composition and drug availability. The interactions—seen for a variety of medications, such as depression, diabetes, and asthma drugs—could help researchers better understand individual differences in drug effectiveness and side effects.