Breast Cancer Metastasis, and Chemo Resistance Gene Identified as Target for Nanoparticle-Based Therapy

University of Virginia Cancer Center researchers identified a gene that is responsible for the spread of triple-negative breast cancer to other parts of the body, and which can render the cancer. The scientists developed a nanoparticle-delivered antibody that demonstrated early indications in mice, which they hope could possibly address both TNBC metastasis, and resistance to treatment and estimate that this strategy of blocking the TRIM37 gene could benefit approximately 80% of TNBC patients.