BioTrove’s sample-prep system will be coupled with Applied Biosystems mass spectrometers.



Applied Biosystems and BioTrove have agreed to combine mass spectrometry technologies to offer the pharmaceutical and biopharmaceutical industries. These services will support high-throughput compound screening and in vitro ADME applications.


The nonexclusive reseller agreement couples BioTrove’s RapidFire™ sample preparation system with any of the following instruments from Applied Biosystems and MDS Analytical Technologies, the joint venture partner: the API 5000™ and API 4000™ triple quadrupole mass spectrometers and the 4000 QTRAP®, which is a hybrid triple quadrupole/linear ion trap mass spectrometer.


BioTrove will offer its customers a single-service plan for complete workflow support. The plan will include application support, instrument maintenance, Applied Biosystems’ Smart Monitoring Service, and other types of support.


BioTrove points out that its RapidFire system allows mass spectrometry to integrate seamlessly into existing high-throughput infrastructure due to its automated sample prep at a rate of six to eight seconds per sample, compared with HPLC systems may require several minutes per sample.


The API 5000 and API 4000 platforms provide high sensitivity and selectivity in analysis, according to Applied Biosystems. The 4000 QTRAP offers quantitative and qualitative analysis within a single system. It enables applications that cannot be done by any other instrument on the market, the company adds.








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