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February 1, 2014 (Vol. 34 , No. 3)

Cytomegalovirus DNA Linearity Panel

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SeraCare Life Sciences

A linear challenge panel for quantifying cytomegalovirus (CMV) viral load is available. Named the CMV DNA AccuSpan™ Linearity Panel, it consists of nine members—seven positive members representing serial log dilutions of cultured virus in CMV DNA negative diluent; one negative member prepared from the diluent; and one member of diluent to perform additional dilutions as desired. The results of the CMV test were calibrated to the WHO International CMV Standard for Nucleic Acid Amplification Techniques and show a nearly 1:1 linearity. The addition of extra diluent is meant to allow end users to perform sensitivity challenges in their own laboratories. (Regulatory bodies require dilutions performed in a lab be made with the same diluent as the panel.)

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