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June 15, 2012 (Vol. 32 , No. 12)

Cell-Based Kinase Assays

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Cisbio Bioassays

Three kinase assays are now available as part of a cell-based kinase screening platform. Phospho-STAT3 (signal transducer and activator of transcription 3) (Tyr705), Phospho-p38 MAPK (Thr180/Tyr182), and Phospho-IKKβ (Ser177/Ser181) involve targets that are associated with many diseases including cancer, rheumatoid arthritis, Crohn disease, pulmonary fibrosis, and acute lung injury. Specifically, the assays provide a target in a physiological environment and aid in the analysis of signaling pathways in response to drug treatment.

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