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May 15, 2011 (Vol. 31 , No. 10)

3-D DNA Chips

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Toray Industries

3D-Gene™ products are a range of three-dimensional DNA chips for use in microarray analysis. The new microarrays utilize several features to help enhance assay sensitivity, providing a useful platform for working with low-abundance targets such as microRNAs or difficult samples such as FFPE tissue specimens. Each chip is composed of a black resin that reduces background fluorescence, while probes are attached to three-dimensional microcolumns on the surface. In combination, these factors define the spot morphology. The columns are also surrounded by microbeads that are encapsulated on the chip and can be agitated to ensure homogenous sample distribution during the hybridization process. These properties aid in increasing signal-to-noise ratio, accuracy, reproducibility, and sensitivity. The chips are compatible with current array scanning.

  • Toray Industries
  • Nihonbashi Mitsui Tower
  • Nihonbashi-Muromachi 2-chome, Chuo-ku
  • Tokyo , 103-8666

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