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New and unique nanomedicines are constantly being created as the list of potential nanoparticle carrier systems grows to include proteins, lipids, polymers, small molecules, and more. When producing nanomedicines like lipid nanoparticles, sample integrity and recovery are among the biggest challenges during production and scale-up. Big Tuna replaces complex, one-at-a-time methods by fully automating buffer exchange and concentration, exchanging samples faster and more consistently without compromising sample integrity or recovery.

When it comes to quantifying payloads, most solutions are stuck in the past, often needing a complex workflow to disrupt carriers and make readings against standard curves. Stunner learns and remembers everything about the UV/Vis absorbance of a particle—from carrier to payload to turbidity—making Stunner crazy simple in its unique ability to quantify payloads for any one-of-a-kind nanoparticle carrier. Since quantification is UV/Vis-based, you can skip the complicated workflows, costly dyes, and wasteful standard curves to get answers in minutes with just 2 µL of sample. Beyond quant, Stunner adds low volume, high-throughput DLS to deliver size and aggregation info earlier in the development process on more samples and with smaller volumes.

This GEN webinar will show that whether a nanoparticle’s payload is RNA, DNA, protein, or another API, Big Tuna handles buffer exchange and concentration while Stunner delivers dye-free, label-free, standard-free, hassle-free quant.

A live Q&A session followed the presentation, offering a chance to pose questions to our expert panelist.

Nelis Denys
Nelis Denys
Product Manager, Lunatic & Stunner
Unchained Labs