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Synthetic biology is a cutting-edge interdisciplinary field of research that incorporates the fundamentals of traditional genetic engineering, biophysics, and systems biology, while mixing in elements of computer aided design and mathematical modeling, yielding a truly unique approach to constructing biological machines. This approach focuses on producing engineered organisms to perform new and useful functions. It aims to develop technologies, methods, and biological components that will ultimately make the engineering of biology safer and more reliable.
In order to realize its full potential, synthetic biology requires novel approaches to biomolecule production that can increase manufacturing speeds, reduce working volumes and decrease human handling errors—a scenario that contributes to substantial workflow cost savings. Acoustic droplet ejection (ADE) technology is a liquid-handling technique that uses focused ultrasonic energy to eject small droplets from liquid, filling the demand set by synthetic biology for increased miniaturization at ultra-high throughput screening speeds. Furthermore, since acoustic liquid handling requires no tips, pins, or nozzles the risk of sample cross-contamination is almost zero and overall production costs are lowered due to a dramatic decrease in consumable waste.
In this GEN webinar our panelists will present how acoustic liquid handling technology complements synthetic biology approaches and provide experimental data from streamlined workflows that show increases to overall productivity.
Randy Dyer, Senior Product Marketing Manager at Labcyte, will introduce concepts underlying advanced acoustic liquid handling, how they are applicable toward many aspects of laboratory work and how Labcyte’s Echo® 500 series liquid handler can aid in streamlining production workflows.
“Patrick” Yizhi Cai, Ph.D., Co-Director of the Edinburgh Genome Foundry at the University of Edinburgh, will discuss his work on the synthesis of artificial yeast chromosomes and how acoustic liquid handling technology has aided his research by significantly increasing the speed at which he can genotype synthetic products and downscale the volume of DNA assembly dramatically.
Who Should Attend
- Molecular biologists
- Researchers interested in synthetic biology
- R&D scientists
- High-throughput screening scientists
- Scientists developing biopharmaceutical analytical workflows
You Will Learn
- Why yeast is an excellent organism for synthetic biological engineering and its important healthcare implications.
- Design principals behind synthetic yeast genomes.
- How ADE technology can increase the speed and accuracy of traditional liquid-handling methods and how it is being used in yeast synthetic biology research.
Panelists
“Patrick” Yizhi Caii, Ph.D.
Co-Director, Edinburgh Genome Foundry,
University of Edinburgh
Randy Dyer
Senior Product Marketing Manager
Labcyte