Kathy Vuksanaj

Kathy Vuksanaj wrote a new post, Perspectives Toward a Treatment for Early Onset Alzheimer’s Disease 2 days, 14 hours ago

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When small companies have big ideas that could benefit countless patients, they must find partners to expand the spectrum of their expertise and infrastructure to help them test these ideas […]

Kathy Vuksanaj wrote a new post, Ultra-Sensitive IL-11 Target Engagement Assay Development 5 days, 11 hours ago

Broadcast Date: August 25, 2022Time: 8:00 am PT, 11:00 am ET, 17:00 CET

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Interleukin-11 (IL-11) is an interesting and unique pleiotropic cytokine, originally characterized as a h […]

Kathy Vuksanaj wrote a new post, Biobanking Embraces Specialization and Interdependence 5 days, 20 hours ago

Although the word “biobanking” emerged in the 1990s, it has yet to acquire a set meaning. For some, the word encompasses the long-term storage functions fulfilled by biorepositories; for others, it refers to the […]

Kathy Vuksanaj wrote a new post, SARS-CoV-2 Cell Surface Nucleocapsid Protein Modulates Innate and Adaptive Host Immunity 6 days, 11 hours ago

Broadcast Date: August 24, 2022Time: 8:00 am PT, 11:00 am ET, 17:00 CET

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Despite the unprecedented global response to SARS-CoV-2, which has generated over 250,000 publications in tw […]

Kathy Vuksanaj wrote a new post, Challenges and Considerations for mRNA Therapeutic Development 6 days, 13 hours ago

Broadcast Date: August 23, 2022Time: 8:00 am PT, 11:00 am ET, 17:00 CET

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Due to its extreme potential to revolutionize the biopharma industry, the benefits of mRNA as a novel th […]

Kathy Vuksanaj wrote a new post, Phage Therapy: Thwarting Antibiotic Resistance and Saving Lives 2 weeks, 2 days ago

Martha Clokie, PhDProfessor of MicrobiologyUniversity of Leicester

Graham Hatfull, PhDProfessor of BiotechnologyUniversity of Pittsburgh

Ivan Liachko, PhDChief Executive OfficerPhase […]

Kathy Vuksanaj wrote a new post, Modernizing Your In Vivo R&D Programs 2 weeks, 3 days ago

Broadcast Date: August 16, 2022Time: 8:00 am PT, 11:00 am ET, 17:00 CET

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In vivo studies are an essential component of biopharmaceutical R&D that help teams understand drug pha […]

Kathy Vuksanaj wrote a new post, Bioprocessing 4.0 Hinges on Monitoring and Control Technology 2 weeks, 4 days ago

Reaching Bioprocessing 4.0 depends on advanced methods of monitoring and control. For an update on these methods, GEN has organized this roundtable discussion. It presents the insights of four experts from three […]

Kathy Vuksanaj wrote a new post, Lonza’s Perspective on Process Monitoring and Control 2 weeks, 5 days ago

By Mirza Jakupovic

Currently, bioprocess monitoring and control systems rely on infrequent and time-consuming offline sampling methods. This can lead to loopholes in data and major gaps in knowledge, as […]

Kathy Vuksanaj wrote a new post, Digital Twins and AI Reshape Biopharmaceutical Manufacturing 2 weeks, 5 days ago

The quality of a drug product is determined by the manufacturing line. Preclinical assessments and clinical trials provide an indication of safety and efficacy, but it is the manufacturing process that ultimately […]

Kathy Vuksanaj wrote a new post, The State of Phage Therapy Research 2 weeks, 6 days ago

The use of viruses to treat bacterial infections has great potential, but it still faces challenges. To shed light on the state of the field, GEN consulted Martha Clokie, PhD, professor of microbiology at the […]

Kathy Vuksanaj wrote a new post, Phage Therapy Starts Realizing Its Long-Deferred Potential 2 weeks, 6 days ago

By Katarina Zimmer

Soon after bacteria-killing viruses were independently discovered by English physician Frederick Twort in 1915 and by French microbiologist Felix d’Herelle in 1917, the tiny microbes were s […]

Kathy Vuksanaj wrote a new post, City of Vacaville: Providing Development Opportunities for the Biotech Industry 2 weeks, 6 days ago

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Why is Vacaville, CA, focused on becoming a major regional biomanufacturing hub?

Vacaville has been a biomanufacturing hub since the first large-scale manufacturer […]

Kathy Vuksanaj wrote a new post, Optimizing Cell Line Construction: How to Find More Needles in a Haystack 3 weeks, 2 days ago

Originally Aired: August 9, 2022Time: 8:00 am PT, 11:00 am ET, 17:00 CET

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To meet the demands of ever shorter cell line construction timelines, especially in manufacturing complex protein t […]

Kathy Vuksanaj wrote a new post, Identifying the Best AAV Vectors for Safer, More Potent, and Reliable Therapeutic Performance 3 weeks, 5 days ago

Broadcast Date: August 31, 2022Time: 8:00 am PT, 11:00 am ET, 17:00 CET

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Gene therapy addresses the underlying genetic anomaly by correcting the mutation using gene-editing tools d […]

Kathy Vuksanaj wrote a new post, Optimal Cryogenic Cooling 1 month ago

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The Goldilocks principle—stating that some things need to be “just right”—is incomplete. Exactly how is “just right” reached? This omission is particularly vexing in cryopreservation: one can be s […]

Kathy Vuksanaj wrote a new post, Living in a Spatial World: Characterizing the Immune Environment in Tumors 1 month ago

Originally Aired: August 3, 2022Time: 8:00 am PT, 11:00 am ET, 17:00 CET

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Immunotherapy has transformed the treatment of metastatic and recurrent solid tumors. Advances in technology in th […]

Kathy Vuksanaj wrote a new post, Discovering the ‘Paradigm Shift’ Associated With Chemoresistance in Acute Myeloid Leukaemia 1 month, 1 week ago

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‘It was amazing to discover that AML evolution is mainly driven by methylation alterations that affect low density CpGs regions in the gene body of master transcription f […]

Kathy Vuksanaj wrote a new post, The Genomic and Epigenomic Landscape of HPV in Cervical Cancer 1 month, 1 week ago

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Cervical cancer is caused almost exclusively by the human papilloma virus (HPV) and has a large mortality burden, especially in the developing world. HPV has a 7.9 kb […]

Kathy Vuksanaj wrote a new post, The ‘Multi-tool’ for Translational Cancer Research 1 month, 1 week ago

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See how cancer research can benefit from accessible, targeted long nanopore reads which facilitate a comprehensive analysis of multiple variant types across genomics, […]