Cannabis Compound Shown to Cause Developmental Defects in Genetically Susceptible Mice

Scientists at the Icahn School of Medicine at Mount Sinai have shown that the cannabis compound, Δ9-tetrahydrocannabinol (THC), can act as a conditional teratogen, and can cause birth defects in genetically preconditioned mice that carry a Hedgehog signalling pathway-related gene mutation. They suggest that their findings have significant public health relevance, and suggest that women should not consume cannabis, during pregnancy, or while trying to get pregnant.