GEN Magazine

Volume 42, Issue No. 09, September 2022

We’ve all heard that every picture tells a story. But what if the picture is a stained or labeled tissue slide? In that case, the picture may be too sketchy to tell the sorts of stories many scientists would like to hear—stories about intracellular processes and intercellular communications. Not to worry! Tissue slides are now giving us more detailed information thanks to spatial omics technology. Indeed, there is so much information that we may have difficulty making sense of it all. And it is here that GEN has a story to tell. The story’s theme? The search for meaning. The story’s heroes? Intrepid scientists and biomarker developers. The supporting characters? Giant data sets and machine learning software. That’s all we’ll say for now. (No spoilers here.) But we should note that spatial omics is part of a new scientific genre, one that’s all about data-driven insights. As this issue of GEN shows, such insights are being sought in cancer research, precision medicine, and gene editing applications.

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Website Content from This Issue

Spatial Technology Offers Spectacular Insights

Mouse small intestine

Liquid Biopsies Guide the Development of Cancer Drugs

Cancer cells on dna stand background

Tumor-Informed Liquid Biopsies to Transform Oncology Drug Development


Recombinant Proteins Benefit the Clinical Diagnostic Industry

Scripps Laboratories scientist

Host Cell Proteins Can Be Eliminated More Strategically

3d illustration proteins

Host Cell Protein Analysis: Is Above and Beyond Just Enough?

Release of monoclonal antibodies, illustration

Key Points from the FDA’s Guidance for CAR T-Cell Products

Parexel staff with white board

CRISPR Technology Turns 10, Rises to New Challenges

Genetic engineering, GMO and Gene manipulation concept. Hand is inserting sequence of DNA.  3D illustration of DNA.

Precision Medicine Marshals Its Resources


Empowering Next-Generation Precision Genetic Medicines

disease-causing mutations

An Integrative Approach to Probing Transient Protein Structures in Cell Extracts

Modern Medical Research Laboratory: Two Scientists Wearing Face Masks use Microscope, Analyse Sample in Petri Dish, Discuss Innovative Technology. Advanced Scientific Lab for Medicine, Biotechnology

3D Cell Culture—Capturing Complexity with More Consistency

The Corning Life Sciences MatriBot®

CRISPR Revolution in Cell and Gene Therapy

Synthego lab

Choosing the Right Spatial Technology

SMI Raw Data

Middlesex County, NJ: Where Life Sciences Companies Thrive

Rutgers Innovation

Seamlessly Upgrade Your CRISPR Toolbox From Cas9 to Cas-CLOVER™

Works Seamlessly with Existing gRNA Infrastructure

The AI-Led Engine Advancing Our Understanding of Rare and Ultra-Rare Diseases

Medicine doctor touching electronic medical record on tablet. DNA, capsules

How to Maximize the Potential of CRISPR


Optimized Lentiviral Vectors


UltraViolet Dyes for Multiplex Flow Cytometry

Bio-Rad Laboratories UltraViolet Dyes

Optimized Microplate for Cannabis Sample Processing


cBioPortal for Cancer Genomics


Single C Analyzer


Charles River Laboratories