GEN Magazine

Volume 41, Issue No. 06, June 2021

June 2021 cover image

Crossing uncharted spaces can lead to unexpected discoveries. Just ask Columbus. Today, the new world that awaits is in neuroscience. Different kinds of brain maps, such as gene expression maps and functional MRI maps, may soon become integrated, prompting explorations that are as adventurous, in their own way, as sailing west to reach Asia used to be. And as new pathways become familiar, the pathological mechanisms behind neurological dysfunctions may be erased, much like sea dragons were removed from Renaissance maps. Other explorations discussed in this issue of GEN are no less exciting. For example, biomanufacturing, precision medicine, and multiomics are being remapped to reflect the rise of continuous processing, secure data exchange architectures, and proteomics, respectively. Also, this issue surveys the gene and cell therapy scene from the vantage point afforded by ASCGT 2021. Finally, this issue presents a glimpse over the biopharma horizon, where operational boundaries between sponsors and contractors are fading.

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Website Content from This Issue

Overview of the Synthetic Biology Market

Genetic engineering and digital technology concept.

Brain Maps May Reveal the Origins and Paths of Neurological Dysfunction

Brain Map

Mapping How the Brain Organizes Semantic Activity

Brain and data

CROs Shift from Hired Hands to Trusted Partners

Scientists working in laboratories

CDMOs Go Digital to Gain a Competitive Edge


Good CROs Make Dream Teams, Great CROs Make Dynasties

Doctors working in laboratory during COVID-19

Adaptability of CDMOs Sorely Tested by COVID-19

scientist with bioreactor

Pressure Builds to Elevate Continuous Bioprocessing

Scientist in a clean room laboratory

Proteomics Broadens the Multiomics Outlook

Precision Medicine Expands the Clinic’s Boundaries

Genetic testing

ASGCT 2021: The Gene Therapy Show Must Go On

Sangamo Therapeutics lab

A Unique E. coli—Based Secretion System

E. coli bacteria was used to study the sequences in DNA where the risk for mutation is significantly elevated. [National Institute of Allergy and Infectious Diseases]

An Optimized High-Content Imaging Workflow for 3D Spheroid Cell Models

In Sphero

A Pipeline Isn’t a Story: Five Lessons for Biopharma Branding

Medication bottles

Streamlining the Spatial Transcriptomics Workflow

Improve Quality of Engineered Cell Therapies with Functional Proteomics

Smooth Collaboration Between CDMOs and Tech Providers Boosts AAV Manufacturing Efficiency

Flexible, Fully Integrated Bioprocessing Ecosystems for Streamlined Biotech R&D

Vaccine Innovations—Then and Now

vial and syringe

Drug Hunters Driven by a Passion for Science

Atomic Force Microscope

System to Control Gas Composition and Humidity

Serological Pipettor

Recovery of Purified RNA

Orange NMR

Neurology Pocketbook

Mission to Mars AR

EE Toolkit

Retrons Display Genome Editing Strengths Even CRISPR Might Envy

Bacteriophage Infecting Bacterium

Experimental Drug Boosts Brain Cell Cleaning to Reverse Alzheimer’s Disease Symptoms in Mice