GEN Magazine

Volume 41, Issue No. 04, April 2021

GEN April 2021 cover image

Biotechnology is increasingly about crunching the numbers. Thankfully, the crunching is being performed by computational platforms, including artificial intelligence platforms, whether they are generating single-cell analyses, sifting through biomarker data, suggesting physicochemical tweaks to drug candidates, finding new uses for old drugs, or optimizing drug manufacturing processes. All of these applications are covered in the April issue of GEN, which emphasizes that in every instance, computational resources, however sophisticated, cannot accomplish much on their own. Still, as this issue of GEN suggests, there is enormous potential in combining the complementary strengths of computers and humans.

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Website Content from This Issue

A Genomics Event: Missing the Sunshine but Basking in Science

NanoString’s GeoMx Digital Spatial Profiler generated image

Funding the Next Generation of Cancer Therapies


AI in Drug Discovery Starts to Live Up to the Hype

Artificial Intelligence

Addressing the Top Five Challenges to AAV-Based Gene Therapy with ddPCR


The Next Generation of Cell Factories for Viral Vector Production

Catalent's manufacturing facility in Harmans, MD

Gene Therapy Adopts New Tools to Guarantee Quality

Lonza lab

Gene Therapies Receive a Shot in the Arm

3D-Bioprinted Cell Therapy and Disease Modeling Applications


Emerging Trends for Bioprocessing

scientist with bioreactor

CDMOs Embrace Industry 4.0 to Satisfy Customer Demand

BioContinuum Automation & Analytics Platform

Harbingers of Things to Come in Gene Therapy

mouse cerebellum

Powering Perfusion at the Microscale

True Perfusion cassette

New Tools are Democratizing the Life Sciences and Enabling Entrepreneurial Biology

Thomas Ybert, PhD

NIH Panel Advocates Harsh Price for Cline

Efficient Production of rAAV in a Perfusion Bioreactor Using an ELEVECTA® Stable Producer Cell Line

cevec lead image

GEN Interview: Joy Xiaohui Chen, PhD, Discusses a Case Study Designed to Optimize AAV Process Development and Tool Selection

Functional Profiling of CRISPR-Edited Cells Identifies Potent and Durable Immune Therapies


A Revolution in Spatial Biology: the GeoMx® Whole Transcriptome Atlas

NanoString Stain Cover

The Importance of CDMO Flexibility in AAV Manufacturing

Downstream processing

Benchtop Evaporator

Patient-Derived Human Primary Cancer Cells


Robotic System for Ultra-High-Throughput SARS-CoV-2 Testing

Centrifugation BioProcess Container

Methylation Detection System

Automated Liquid Handler

Mitochondrial Stain

Bioreactor Line

Oh Bother

Anatlab Histology

Elocance Articles PDF reader

Adobe Illustrator

Top 10 U.S. Biopharma Clusters 2021

Resilience Boston Allston Plant

OXGENE Eyes Further Growth in Cell and Gene Therapy Services after Acquisition by WuXi AppTec