GEN Magazine

Volume 41, Issue No. 11, November 2021

GEN November 2021 cover

This month, GEN explores the innards of several drug development modalities. Now, “innards” may seem too visceral a word, but it is apt, particularly with respect to our coverage of synbio-based manipulations of the gut microbiome. But then, the phrase “inner mechanisms” would also serve. It is in the spirit of another part of our coverage, an article that describes how developers of synbio therapeutics are being used to install gene circuits and rewire cell signaling pathways. GEN has yet other opportunities to delve deeply: articles that describe how new therapeutics are undoing cancer and neuropsychiatric disorders at multiple levels, how glycomics technologies are supporting precision medicine, how PCR-based clinical applications are expanding beyond COVID-19 diagnostics, and how agricultural applications of gene editing may help us cope with a warming world. And last but not least, GEN describes six up-and-coming COVID-19 vaccines.

Website Content from This Issue

Six Up-and-Coming COVID-19 Vaccines

Inovio Pharmaceuticals lab

More than One Way to Fight Disease with Synbio Drugs


Overview of the Synthetic Biology Market

Genetic engineering and digital technology concept.

Synthetic Biology Brings Programmability to Drug Programs

synthetic biology made by combination of cell and gene code

Undruggable No Longer

Arvinas lab

The Multifaceted Challenge of Modeling Alzheimer’s Disease

Taconic Biosciences lab

Neuropsychiatric Drug Developers Show a Renewed Sense of Purpose


How Gene Editing Can Support Sustainable Agriculture


CRISPR-Cas Can Help Reduce Climate Change

CRISPR - Gloved Hands DNA

The State of Agbiotech

Rows of Iowa soybeans

Glycomics Applications Reinforce Precision Medicine

DNA and medical technology concept, biotechnology, gene recombination

PCR Gains New Powers and Broadens Its Clinical Remit

pcr device

PCR Gains Momentum with New Applications


Could Biobanks Be the New Frontier for Digital Health Research?

Genetic Engineering Digital Tech Concept

Nanocrystals Boost Bioenergetics and Restore Neuronal Health

Using In Vitro–In Vivo Extrapolation to Predict Human Clearance

RNA Coronavirus

Upcoming In Vivo Options for Studies of Addiction and Abuse

gene editing

Building a CAR-T Toolbox for More Comprehensive Assessment of Cell Therapies

leukocytes attacking a cancer cell

Three Key Factors Affecting Single-Cell Transcriptional Analysis

Single-Cell Functional Proteomics

ung cancer cells

Casting a Wider Net: How Spatial Omics Leads to New Discoveries

mouse brain

Overcoming Plasmid DNA Limitations In Advanced Therapy Manufacturing


Aptamers for Targeting 
SARS-CoV-2 Proteins

Six-Color Digital PCR System

SStilla Technologies PCR System

Low Maintenance Evaporator