GEN Magazine

, Volume 39

Website Content From This Issue

Website Content from This Issue

CRISPR Vehicles Break Down Barriers to In Vivo Genome Editing

crispr delivery

For Whom the Perturbed Cell Signaling Pathway Tolls

cell membrane

Metabolomics Technology Navigates Oceans of Data

automated platform developed by Metabolon

Taking Cell Lines to the Bank

digital cell culture technology

Stem Cell Technology: The Only Constant Is Change


Scottish CRO Integrates Drug Discovery and Compound Management

BioAscent Discovery facility

Biobanking Can Boost Scientific Productivity

Cognitive Take on RNA Elevates Biomarker Development, Advances Precision Medicine

RNA Models

Complex Research Calls for Sophisticated Biobanking Tools

Processing samples through the Hamilton Nimbus

Biobanks Manage Diverse Portfolios, Execute Complex Transactions

The Precision Pathology Biobanking Center

Accelerating AAV to the Clinic with Purification Improvements

Genetic engineering and digital technology concept.

Understanding and Overcoming the Immune Response from Synthetic mRNAs

New England Biolabs

Evaluation of a Small-Scale Perfusion Mimic for Intensified Processes

Sartorius lab

The First Cut Is the Deepest

OXGENE workflow

Advanced Technologies for Therapeutic Antibody Discovery

Aldevron Beacon

GEN Interview: Markus Gershater, PhD, CSO, Synthace

Synthace Company Cover

Biobank Automation Considerations

Nigel McMillan

Bridging the Gap between Biobanks and Industry

petri dish

Centralize Your Biorepository Management


Reliable Storage of High-Value Biospecimens


Portable Inverted Microscope

ioLight inverted microscope

Benchtop Sequencing System

DNBSEQ E sequencers

Next-Generation Centrifuge Series

General Purpose Pro Centrifuge Series

Ultra-Clean Deep-Well Plate

Deep-well microplates

One-Step Multiplex Supermix

Reliance One-Step Multiplex Supermix

Heater/Shaker for Use with Automated Pipetting Robots

BrandTech Scientific Teleshake 95 heater/shaker

Advanced 2D Code Reading

Rack Reader DR700

Spiral Evaporator

DrySyn Spiral Evaporator

The Fourth Dimension

The Fourth Dimension screenshot cropped


CRISPR-3D screenshot

Skeletal Anatomy 3D—Quiz and Reference

Skeletal Anatomy 3D screenshot

Idle Human

Idle Human screenshot

Enzyme Discovery May Put Brakes on Parkinson’s Disease

Parkinsons Disease Brain

Top 25 Biotech Companies of 2019

Synthetic Biology Seizes New Ground in Healthcare

CytoSeek Protein and Peptide

Agrigenomics Yields a Next-Gen Cornucopia


Protein-Protein Interactions Get a New Groove On

protein–protein interactions

Machine Learning Enhances Cytometry Analysis

Cytobank’s cloud-based software platform

Biomarker Specialists Team Up, Run Up the Companion Diagnostics Score

At Left. A multiplexed pharmacodynamics assay was developed recently to assess immune checkpoint inhibitor–targeted CD8 activation and tumor colocalization in formalin-fixed paraffin-embedded tissues. The assay, which used oligo-conjugated antibodies supplied by Ultivue, achieved multiplex staining of CD8 (red), CD3z-pY142 (yellow), β-catenin (cyan), and Zap70-pY493 (not shown) on bead-activated CD3 cells from tissue spiked with interferon-γ-induced ACHN tumor cell lines. Staining of β-catenin allowed tumor cells to be differentiated from immune cells. Arrows point to CD8 cells that are CD3z-pY142+, indicating T-cell receptor activation.

Scale-Out Plus Single-Use Can Multiply Yields

FlexFactory, GE Healthcare’s single-use technology platform

Surveying the Tear Proteome to Stratify Glaucoma Patients

Opportunities and Challenges in Cell and Gene Therapy Development*

T cells around a cancer cell

New Double-Stranded Twist on NGS Adds More Depth to Each Run


A Novel Endotoxin-Free Microbial Expression System

Bacillus subtilis

How Effective Buffer Management Facilitates Biopharmaceutical Production

scientists in clean room

Improve your Gene Editing Success with CRISPR-SNIPER Technology


Next-Generation Centrifuge

Thermo Fisher Scientific Centrifuge

RenMab™ Mouse Set to Become the Leading Platform for Generating Human Antibodies

White mouse in laboratory


Animal Tracker screenshot

Rubella Virus–Like Particles

The Native Antigen Company's Rubella VLP

Single-Tube Code Reader

Micronic Single Tube Reader

Protein Clean-Up Microplate

Porvair P3 Microplate

Human Coagulation Antigens and Antibodies

The Binding Site Human Coagulation Antigens and Antibodies

Bioinformatics Is the Pathway to Fully Realized Precision Medicine

Genetic Research

Open Ephys

Bloomington Drosophila Stock Center

Bloomington Drosophila Stock Center screenshot

Smart Microscope

Zeiss Smart Microscopes

Brainspan: Atlas of the Developing Human Brain

Brainspan screenshot

Cold Block

Asynt DrySyn ChilliBlock

Automated Cryo-Electron Microscopy Sample Prep

TPP Labtech Cryo Sample Prep System

Better Living through Molecular Neuropharmacology


CRISPR Dx May Help Nix Disease

paper test strip

Modular Bioprocessing Makes Adaptability a Snap

FlexAct automation platform

A Nanomedicine Technology Sampler Pack


In AI We Trust? The Future of Genomic Medicine

Data behind outline of man with DNA surrounding him

GEN October 2019 Digital Supplement

Gene Therapies Are Being Brought to a Wider Audience

suspension culture in MilliporeSigma lab

Wound Healing Facilitated by Birth Tissue Products

proprietary cryopreservation process

Cell Therapy Manufacturing Tries “Building the Plane While Flying It”

Lonza manufacturing suite

Knocking the Rough Edges Off T-Cell Therapy Manufacturing

Mustang Bio laboratory

Energy Transfers Reveal Kinetics of Intracellular Binding

Using Alternating Tangential Flow with Fed-Batch Cultures

Jae Kim, ATF Lab - SU Repligen

Expanding the CRISPR Toolkit

DNA Technologies Assay Tutorial Figure 1

Clinical Variant Analysis for Cancer

ovarian cancer cells


Mendeley app

Polyfunctionality Correlates with In Vivo Response to Immune Checkpoint Inhibitor Therapies

Two women in IsoPlexis lab

Ultracentrifuge Designs Enable Linear Process Scaling

Alfa Wassermann logo

Improving CAR-T Cell Precision Bioprocessing with Functional Proteomics

Isoplexis' ISO Light

Biologically-Validated A.I. Yields Breakthrough in Cardiovascular Disease

Tom Chittenden

E. coli Host Cell Protein Kit

host cell protein (HCP) kit

Hybrid Tubes

hybrid tubes

Controlled Rate Freezer

BioCool V40

Next-Generation Light Scattering: Determining AAV Titer with Multi-Angle Dynamic Light Scattering

Malvern Panalytical Empyrean Students

The Most Published Models in Neurobiology

Jackson Labs sponsored content mouse model

Ultra-Flat, Quartz Bottomed Microplates

Black Krystal UV quartz-bottomed microplates

Monoclonal Antibody for Rubella Testing

Rubella MAb R22T

Plate Reader

Spark® Cyto

Single-Use, Fixed-Bed Bioreactors


Microsatellite Instability ddPCR Assay

Droplet Digital PCR Microsatellite Instability (MSI) RUO assay

Mysteries of Fractal

Mysteries of Fractal app


CDC app

Wolfram Statistics Course Assistant

Wolfram Statistics Course Assistant app

Reversible TB Gene Mutation Finding May Lead to Improved Therapies

Mycobacterium tuberculosis bacteria

Catalog of Human Gut Bacteria Expected to Advance Microbiome Research

Gut bacteria word collage

Going Viral: The Next Generation of AAV Vectors

Spark Therapeutics technician

Looking Into a Crystal Ball

Ronald G. Crystal, MD,

Liquid Biopsies Intensify Surveillance of ctDNA

Lexent Bio lab

Drug–Drug Interaction Studies Look Beyond CYP Activity

Female scientist pipetting sample into a vial for analytical testing in a lab

3D Bioprinting Makes the Imitation Matrix Real

Rat Lung Epithelial Cells