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GEN – Genetic Engineering and Biotechnology News
GEN Edge
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Drug Discovery
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Infectious Diseases
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GEN Magazine
May 2020 Vol. 40, No. 5
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May 2020
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Website Content from This Issue
News
Gene Therapy Reverses Effects of Heart Failure and Restores Heart Function...
Cancer
Early Cancer Detection Boosted by Molecular Fingerprint
Infectious Diseases
Single Influenza Mutation Could Enable Human-to-Human Transmission
Cancer
Patient Glioblastoma Response to CAR-T Cell Therapy Mirrored in Tumor-Derived Organoids...
News
How Electrical and Calcium Signaling Work as One to Regulate Blood...
Bioprocessing
WHO Seeks Expressions of Interest to Join as Regional Biomanufacturing Training...
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Bringing Advanced Research to Laboratories Worldwide
Cancer
Lymphoma Immunotherapy Enhanced by Enzyme Inhibitor In Preclinical Model, Prompting Pilot...
Cancer
Killer T Cells Programmed for Tissue- and Tumor-Specific Targeting
Genome Editing
StockWatch: ARK Mostly Bullish on CRISPR Therapeutics
Artificial Intelligence
AI Drug Discovery Dataset Tops 100M Cells in Vevo, Parse Partnership
News
Locally Immunoprotective Synthetic Suppressor T Cells Could Reduce Need for Systemic...
Cancer
Its Revolutionary Potential as a Liquid Biopsy Sample
Cancer
Potential Cancer Target Uncovered in Bacterial Toxin
Upcoming
Accelerating Cell and Gene Therapy Development Using Gene Editing Functional Genomics...
Bioprocessing
Cambrex Inks Deal with Lilly to Support Biotech Collaborator Manufacturing
Bioprocessing
Charles River Introduces Global Biotech Incubator Program
Bioprocessing
Amgen Raises NC Investment to $1.5B with Plans for Second Plant
News
Parallel Pathway Leaves Long-Term Memory Unscathed Despite Short-Term Disruption in Mice
Drug Discovery
Alzheimer’s Proteins Identified by Combining Mendelian Randomization and AlphaFold
GEN Live
Wrapping up 2024: GEN’s Editors Reflect on the Past Year and...
Cancer
Tumors Have a Taste for Fructose, If It’s Transformed by the...
Bioprocessing
Samabriva Opens New Plant-Based Biomanufacturing Facility in Belgium
Artificial Intelligence
Machine Learning Promises to Increase Cell Culture Productivity
Bioprocessing
Label-Free HILIC-MS Counts and IDs Subunit Free Thiol in mAbs
Bioprocessing
Multiple Factors Influence Host Cell Protein Levels
Translational Medicine
Super-Resolution Microscopy More Than Pretty Pictures
Drug Discovery
Gene and Cell Therapies Take Aim at Parkinson’s Disease
News
New Organoid With All Three Pancreatic Lineages Mimics Human Pancreas
Artificial Intelligence
Force of Nature: Enveda Raises $130M, Advances Lead Pipeline Candidate
Artificial Intelligence
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Cancer
Cancer Immunotherapy Could Turn Up the Heat on Cold Tumors by...
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Key Drivers of AI Drug Discovery
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Downstream Processing: From Byway to Royal Road
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Weaving Textiles from Recombinant Spider Silk
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Drug Discovery
Tuberculosis Bacteria Vulnerable to Substances from Peat Bog Fungi
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Overcoming the Plague of Counterfeit Medications
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Drug Discovery
Alzheimer’s Study Shows Ketone Bodies Help Clear Misfolded Proteins
Infectious Diseases
Genomic Road Map Pinpoints Markers of Malaria Drug Resistance
Artificial Intelligence
Eppendorf and DataHow Collaborate to Advance Bioprocess Data Development
GEN Edge
Going Public: Doudna’s Dream Team Launches Groundbreaking Sickle Cell Trial
Artificial Intelligence
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Drug Discovery
Novartis, PTC Ink Up-to-$2.9B Huntington’s Disease Collaboration
Infectious Diseases
Gift Ideas for Your Favorite Scientist for the 2024 Holiday Season
Infectious Diseases
Antibiotic Resistance Can Emerge If Bacteria Lose rRNA Modifications
Cancer
CAR T Cells Armed with IL-15 Show Promise in Solid Cancer...
A-Lists
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News
Targeting “Proteolethargy” to Restore Protein Mobility May Represent Therapeutic Approach for...
Cancer
Rare Genetic Disorder Helps Explain Link Between Cancer Immunotherapy and Increased...
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The Locus Coeruleus Acts as a Gatekeeper of Sleep Stages
Cancer
Triggering Necroptosis in Tumor Cells Can Backfire in a Cloud of...
Cancer
Gene Signature for High-Risk Form of Acute Lymphoblastic Leukemia Identified by...
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Alzheimer’s Disease Neurodegeneration Held Back in Mice Treated Using Enzyme Inhibiting...
Infectious Diseases
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Drug Discovery
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![Patient-derived glioblastoma organoid treated with dual-target CAR-T cells. T cells (magenta) infiltrate the tumor organoid and kill tumor cells (blue) (yellow indicates dying cells). [Image by Yusha Sun and Xin Wang from the laboratories of Guo-li Ming and Hongjun Song.]](https://www.genengnews.com/wp-content/uploads/2024/12/low-res-1-218x150.jpeg "Patient Glioblastoma Response to CAR-T Cell Therapy Mirrored in Tumor-Derived Organoids in Real Time")
![The Nicotiana benthamiana tobacco plant is increasingly used for the production of high-value, biologically active molecules. [Wiki Commons]](https://www.genengnews.com/wp-content/uploads/2024/12/Nicotiana_benthamiana_leaf-218x150.jpg "Samabriva Opens New Plant-Based Biomanufacturing Facility in Belgium")
![Tuberculosis Research Section scientists collapse in the bog after a long day collecting sphagnum core samples at Sunkhaze Meadows National Wildlife Refuge in Maine. Front: Clif Barry (Left), Jessica Medrano (Center-Left), Alice Bell (Center-Right), Nelson Reyes Perez (Right), Back: Helena Boshoff (Left), Jenna Andrews (Center), Neha Malhotra (Right) [Vee Tan (CC-BY 4.0, https://creativecommons.org/licenses/by/4.0/)]](https://www.genengnews.com/wp-content/uploads/2024/12/low-res-6-218x150.jpeg "Tuberculosis Bacteria Vulnerable to Substances from Peat Bog Fungi")
![Chronic diseases such as diabetes are on the rise and are costly and challenging to treat. Whitehead Institute Member Richard Young and colleagues have discovered a common denominator driving these diverse diseases, which may prove to be a promising therapeutic target: proteolethargy, or reduced protein mobility, in the presence of oxidative stress. [Jennifer Cook-Chrysos/Whitehead Institute]](https://www.genengnews.com/wp-content/uploads/2024/11/low-res-4-218x150.jpeg "Targeting “Proteolethargy” to Restore Protein Mobility May Represent Therapeutic Approach for Chronic Diseases")
![While boosting T cell cancer-fighting ability, checkpoint inhibitors may reduce the body's production of protective antibodies that fight common infections. [Dr Ofir Shein-Lumbroso]](https://www.genengnews.com/wp-content/uploads/2024/11/low-res-3-218x150.jpeg "Rare Genetic Disorder Helps Explain Link Between Cancer Immunotherapy and Increased Infections")
