GEN – Genetic Engineering and Biotechnology News

Every spatial biology system promises to integrate two kinds of information: 1) gene expression information and 2) spatial information. Different systems, however, may convey gene expression and spatial information in different degrees of detail. For example, gene expression information may be limited to transcriptomic profiles, or it may also encompass proteomic information. And RNA transcript and protein panels may be more or less extensive. Spatial information may be available in low resolution, single-cell resolution, or subcellular resolution. Finally, spatial biology systems may offer greater or lesser throughput, or more or less complicated workflows. To get a handle on all these variables—and to better appreciate the potential of spatial biology—read this GEN Spotlight. It includes thoughtful features from GEN magazine, and helpful advice from NanoString Technologies, a spatial specialist.