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GEN – Genetic Engineering and Biotechnology News
GEN Edge
Featured News
Multimedia
News
Insights
Topics
Artificial Intelligence
Bioprocessing
Cancer
Drug Discovery
Genome Editing
Infectious Diseases
OMICs
Translational Medicine
Magazine
Browse Issues
Subscribe
Multimedia
Summits
Webinars
GEN Live
Learning Labs
Podcasts
Resources
A-Lists
eBooks/Perspectives
Tutorials
Peer-Reviewed Journals
GEN Biotechnology
Re:Gen Open
New Products
Conference Calendar
Subscribe
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GEN Magazine
April 2020 Vol. 40, No. 4
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April 2020
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Website Content from This Issue
News
Parallel Pathway Leaves Long-Term Memory Unscathed Despite Short-Term Disruption in Mice
Drug Discovery
Alzheimer’s Proteins Identified by Combining Mendelian Randomization and AlphaFold
GEN Live
Wrapping up 2024: GEN’s Editors Reflect on the Past Year and...
Cancer
Tumors Have a Taste for Fructose, If It’s Transformed by the...
Bioprocessing
Samabriva Opens New Plant-Based Biomanufacturing Facility in Belgium
Artificial Intelligence
Machine Learning Promises to Increase Cell Culture Productivity
Bioprocessing
Label-Free HILIC-MS Counts and IDs Subunit Free Thiol in mAbs
Bioprocessing
Multiple Factors Influence Host Cell Protein Levels
Translational Medicine
Super-Resolution Microscopy More Than Pretty Pictures
Drug Discovery
Gene and Cell Therapies Take Aim at Parkinson’s Disease
News
New Organoid With All Three Pancreatic Lineages Mimics Human Pancreas
Artificial Intelligence
Force of Nature: Enveda Raises $130M, Advances Lead Pipeline Candidate
Artificial Intelligence
Lonza Expands Smart Capsule Offering for Companies Developing Oral Delivery Solutions...
Cancer
Cancer Immunotherapy Could Turn Up the Heat on Cold Tumors by...
Artificial Intelligence
Key Drivers of AI Drug Discovery
OMICs
Illumina’s Jacob Thaysen Describes His First Year as CEO
Bioprocessing
Downstream Processing: From Byway to Royal Road
Genome Editing
Weaving Textiles from Recombinant Spider Silk
News
Molecular Blueprint Could Redesign Parkinson’s Disease Therapeutics
Drug Discovery
Tuberculosis Bacteria Vulnerable to Substances from Peat Bog Fungi
Sponsored
Simple and Precise pDNA Analytics and Quality Control
Sponsored
Bringing Advanced Research to Laboratories Worldwide
Sponsored
Empowering Scientific Research with Nextflow + AI
News
Stem Cell Behavior Influenced by PIEZO-Dependent Mechanosensing
Drug Discovery
Alzheimer’s Study Shows Ketone Bodies Help Clear Misfolded Proteins
Infectious Diseases
Genomic Road Map Pinpoints Markers of Malaria Drug Resistance
Artificial Intelligence
Eppendorf and DataHow Collaborate to Advance Bioprocess Data Development
GEN Edge
Going Public: Doudna’s Dream Team Launches Groundbreaking Sickle Cell Trial
Artificial Intelligence
AI Outperforms Experts in Neuroscience Study Predictions
Drug Discovery
Novartis, PTC Ink Up-to-$2.9B Huntington’s Disease Collaboration
Infectious Diseases
Gift Ideas for Your Favorite Scientist for the 2024 Holiday Season
Infectious Diseases
Antibiotic Resistance Can Emerge If Bacteria Lose rRNA Modifications
Cancer
CAR T Cells Armed with IL-15 Show Promise in Solid Cancer...
A-Lists
Ten Companies to Watch in AI Drug Discovery
A-Lists
Six Companies Worthy of Note in AI Drug Discovery
News
Targeting “Proteolethargy” to Restore Protein Mobility May Represent Therapeutic Approach for...
Cancer
Rare Genetic Disorder Helps Explain Link Between Cancer Immunotherapy and Increased...
News
The Locus Coeruleus Acts as a Gatekeeper of Sleep Stages
Cancer
Triggering Necroptosis in Tumor Cells Can Backfire in a Cloud of...
Cancer
Gene Signature for High-Risk Form of Acute Lymphoblastic Leukemia Identified by...
News
Alzheimer’s Disease Neurodegeneration Held Back in Mice Treated Using Enzyme Inhibiting...
Infectious Diseases
Novel Mechanism Unraveled in DNA Gyrase, Opening Pathways for Antibiotic Therapeutics
Drug Discovery
Bitter Taste Receptor Engages Compounds Not Just Outside the Cell, but...
Drug Discovery
Inceptor Binds Excess Insulin and Directs It Toward Degradation
Drug Discovery
Bridgebio’s Attruby, to Treat Heart Condition ATTR-CM, Receives FDA Approval
Artificial Intelligence
Xiaorong He on Boehringer Ingelheim’s Investments in AI, Broader Applications in...
Drug Discovery
Trump to Nominate Makary for FDA Commissioner
Drug Discovery
StockWatch: Moderna Seeks to Reassure Investors on RFK Jr.
News
Nanoparticles for mRNA Delivery Get an Edge via Chemically Evolved Lipids
News
snoRNA Target Discoveries Could Lead to Potential Therapeutic Strategies
News
Repair Proteins Collaborate in “Hubs” to Repair DNA Damage
News
Polygenic Risk Scores Found to Predict Dilated Cardiomyopathy in General Population
Insights
Squid Game: Direct Drug Delivery Into GI Tract Using Cephalopod-Inspired Capsules
Bioprocessing
Thermo Fisher’s Accelerator Expands CRO, CDMO Services
Drug Discovery
Novartis Buys Kate Therapeutics, Expanding in Neuro Gene Therapy
Artificial Intelligence
Cmbio Launches to Provide a Centralized Hub for Microbiome and Metabolomics...
Artificial Intelligence
Trans-Atlantic Triumph: AI Drug Pioneers Recursion, Exscientia Combine
Infectious Diseases
Human Antibody Discovery May Point to Vaccines Protecting Against Severe Malaria
Upcoming
Integrated Strategies to Accelerate Pre-Clinical Development of Antibody-Drug Conjugates
Infectious Diseases
Antibiotic Compound, Darobactin, Shows Potency in Multiple Models
Bioprocessing
Lonza Completes First GMP Batch at Next-Generation Mammalian Manufacturing Facility
Cancer
Spatial and Single-Cell Data Combined to Create Comprehensive Cell Map of...
Bioprocessing
Oxygen Control Improves Models of Liver Disease
Bioprocessing
Waters Embraces Integrated Software for Multispecific Analytics
Bioprocessing
New Singapore mRNA Facility Aims to Automate Manufacturing
Bioprocessing
Two-Step M6P Antibody Conjugations Sans Enzyme Remodeling
Drug Discovery
Schrödinger, Novartis Ink Up-to-$2.3B Collaboration, Software Agreement
Cancer
Aggressive Tumor Growth in Drug-Resistant Prostate Cancer Driven by Enzyme
Bioprocessing
Asimov and RevOpsis Therapeutics Ink Licensing Deal for Multispecific-Expressing Cell Line
Bioprocessing
Abzena Expands Analytical Capabilities to Include GMP Cell-Based Potency Testing
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![The Nicotiana benthamiana tobacco plant is increasingly used for the production of high-value, biologically active molecules. [Wiki Commons]](https://www.genengnews.com/wp-content/uploads/2024/12/Nicotiana_benthamiana_leaf-218x150.jpg "Samabriva Opens New Plant-Based Biomanufacturing Facility in Belgium")
![Tuberculosis Research Section scientists collapse in the bog after a long day collecting sphagnum core samples at Sunkhaze Meadows National Wildlife Refuge in Maine. Front: Clif Barry (Left), Jessica Medrano (Center-Left), Alice Bell (Center-Right), Nelson Reyes Perez (Right), Back: Helena Boshoff (Left), Jenna Andrews (Center), Neha Malhotra (Right) [Vee Tan (CC-BY 4.0, https://creativecommons.org/licenses/by/4.0/)]](https://www.genengnews.com/wp-content/uploads/2024/12/low-res-6-218x150.jpeg "Tuberculosis Bacteria Vulnerable to Substances from Peat Bog Fungi")
![Chronic diseases such as diabetes are on the rise and are costly and challenging to treat. Whitehead Institute Member Richard Young and colleagues have discovered a common denominator driving these diverse diseases, which may prove to be a promising therapeutic target: proteolethargy, or reduced protein mobility, in the presence of oxidative stress. [Jennifer Cook-Chrysos/Whitehead Institute]](https://www.genengnews.com/wp-content/uploads/2024/11/low-res-4-218x150.jpeg "Targeting “Proteolethargy” to Restore Protein Mobility May Represent Therapeutic Approach for Chronic Diseases")
![While boosting T cell cancer-fighting ability, checkpoint inhibitors may reduce the body's production of protective antibodies that fight common infections. [Dr Ofir Shein-Lumbroso]](https://www.genengnews.com/wp-content/uploads/2024/11/low-res-3-218x150.jpeg "Rare Genetic Disorder Helps Explain Link Between Cancer Immunotherapy and Increased Infections")
![Lonza's Portsmouth facility. [Lonza]](https://www.genengnews.com/wp-content/uploads/2024/11/Lonza-Portsmouth-218x150.jpeg "Lonza Completes First GMP Batch at Next-Generation Mammalian Manufacturing Facility")
