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May 1, Vol. 28, No. 9

  • Feature Articles

    • GPCRs Remain “Hot” Drug Targets
    • Elizabeth Lipp
    • GPCRs represent the largest family of genes expressed in the human genome, according to Jeremy Richman, PhD, associate director, cardiovascular biology, at Arena Pharmaceuticals “Their cell membrane localization, the diversity of tissue expression, and the fact that they have the ... more »
    • Bioprocess Advances Aim to Streamline Operations
    • Vicki Glaser
    • Thousands of professionals from the pharmaceutical and biopharmaceutical industries gathered at “Interphex” in Philadelphia on March 26–28 Educational presentations, workshops, and the opportunity for companies to display and demonstrate their latest products, technologies, and service offerings spanned the four major ... more »
    • Quantification & Identification in Proteomics
    • Vicki Glaser
    • Charles Cooney, PhD, Robert T Haslam professor of chemical engineering at Massachusetts Institute of Technology (MIT), opened the recent “Label-Free Quantification and Identification for Proteomics” symposium by defining the “proteomics gameplan,” which is determining how a cell responds to its ... more »
    • Tools for Protein Structure Characterization
    • K. John Morrow Jr.
    • A formidable array of techniques allows researchers to describe the properties of protein molecules While nucleic acids are much more restricted in their structural variations, the universe of possible combinations for the 20 basic amino acids permits virtually unlimited variation ... more »
    • Versatility Concerns Impact Facility Design
    • Angelo DePalma
    • Among the uncertainties in biotechnology, constructing a new facility is perhaps the riskiest venture of all Plants must be constructed in anticipation of, rather than in response to, a product’s success As a consequence, developers of biological products are hedging ... more »