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April 15, Vol. 27, No. 8

  • Feature Articles

    • Company Update: Banking on Human Embryonic Stem ...
    • Anyone who has followed progress in human stem cell research recognizes that funding from private and public entities will be crucial for advancement Thanks to a high-profile publicity and education campaign, California voters approved Proposition 71, the $3-billion California Stem ... more »
    • [email protected] Adopts PlayStation 3
    • Officials at Sony Computer Entertainment (wwwsonycom) say that PlayStation®3 (PS3™) will have the capability to connect to Stanford University’s [email protected] program, a distributed computing project aimed at understanding protein folding, misfolding, and related diseases... more »
    • Companies Step Up to GPCR Challenge
    • Susan Aldridge, Ph.D.
    • G protein-coupled receptors (GPCRs) are transmembrane proteins that transduce an extracellular signal—ligand binding—into an intracellular signal—activation of G-protein—which in turn activates various key cellular pathways GPCRs represent the largest protein family in the human genome and play a vital role ... more »
    • Harnessing RNAi's Gene-Silencing Power
    • Kathy Liszewski
    • The emerging science of RNAi is tackling early hurdles and making strides to realize its potential for treating diseases ranging from cancer to HIV New advances will be highlighted at Select Biosciences’ “RNAi World Congress” conference later this month in ... more »
    • Techniques for Characterizing Biologics
    • Aicha Otmani
      Fenton Fong
    • The development of protein-based pharmaceuticals is increasing, and the need for complete characterization of these molecules requires sophisticated techniques Fortunately, significant advances in analytical technology have provided powerful tools for the biotechnology and pharmaceutical industry to assess the batch-to-batch quality ... more »
    • Enterprising Polymer Delivery Methods
    • Vicki Brower
    • A new delivery system for vaccines using biodegradable polymer microspheres may reduce the need for booster shots, as well as stimulate cellular-mediated immunity—an immune response not activated in traditional vaccines Iowa State University researchers reported these findings at the recent ... more »
    • Biosimilars Jumpstart Biotech in India
    • Nalini Motwani
    • India is poised for growth in biotechnology with an abundance of government initiatives and biotech parks under construction in cities like Hyderabad, Bangalore, and Pune Biotech professionals, including many CEOs of Indian companies, convened recently in HiTech City, near Hyderabad, ... more »
    • Moving Immunology Research Forward
    • Alan Koop
    • Immunology and, more specifically, mechanisms of immune tolerance have long been a major focus of biomedical research For decades, scientists have puzzled over the intricate molecular pathways and mechanisms of cellular interactions involved in the immune response It was recognized ... more »
  • Columns

    • Acadias CNS Pipeline Propels Growth
    • Querida Anderson
    • About a month ago, Acadia Pharmaceuticals’ (wwwacadiapharmcom) value more than doubled in a matter of days On March 19, the day it reported positive results for its Phase II schizophrenia co-therapy trial, shares soared 86% to $1249 Since then, Acadia ... more »
    • SynCo Bio Partners Is Poised for Expansion
    • Carol Potera
    • Although there are numerous contract manufacturing organizations (CMOs) for small molecule drugs worldwide, few CMOs make biopharmaceuticals At SynCo Bio Partners (wwwsyncobiocom), based in Amsterdam, the focus is entirely on the development and manufacturing of biopharmaceuticals in small quantities for ... more »