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August 1, Vol. 38, No. 14

  • Feature Articles

    • Epitope Mapping Orients Immune Interventions
    • MaryAnn Labant
    • Epitope mapping, which identifies antigen regions that serve as binding sites for antibodies, is starting to inform the discovery and development of new therapeutics, vaccines, and diagnostics for a myriad of afflictions including cancer, infectious diseases, and allergic diseases... more »
    • New CRISPR Startups Get a Leg Up
    • Brandon May
    • CRISPR startups, like all high-tech startups, climb Mount Commercialization faster if they get an extra boost, which may come from a unique technology, a compelling application, or a hoard of venture capital Some CRISPR startups, however, benefit from another sort ... more »
    • Commercializing Gene Therapies
    • Layne Martin
    • Gene therapy has the potential to revolutionize the treatment of many cancers and rare diseases Each treatment becomes a personalized drug by re-engineering a patient’s immune cells or by introducing a new or modified gene into the body to help ... more »
  • Tutorials

    • Demonstrating Process Scalability
    • Joe Orlando
    • Development of an industry-scale bioproduction process is a time-consuming, multistep operation that requires extensive biological and engineering expertise Although the generation of unique recombinant cell lines hinders development of standard platforms, reduction of variables in cell lines, cell culture media, ... more »