French microbiologist Emmanuelle Charpentier, PhD, has played a critical role in launching the field of CRISPR gene editing while moving between laboratories and countries in her search for a stable and independent research environment. While working at Umeå University, she collaborated with another CRISPR pioneer, Jennifer Doudna, PhD, a professor at the University of California, Berkeley, to show that an RNA-guided CRISPR enzyme, Cas9, could introduce double-stranded breaks in targeted DNA sequences. This work culminated in a classic paper that appeared in Science in 2012 and listed Charpentier and Doudna as co-corresponding authors.
Since then . . .