Home Magazine April 2019 Vol. 39 No. 4 Finding Her Niche: An Interview with Emmanuelle Charpentier

Finding Her Niche: An Interview with Emmanuelle Charpentier

The famed researcher recalls her pioneering work on CRISPR-Cas9’s guidance system, and foresees hitting clinical targets

Emmanuelle Charpentier, PhD
Emmanuelle Charpentier, PhD's, contributions have been heralded by the scientific community and celebrated with dozens of prestigious awards. [Kevin Davies, PhD]

French microbiologist Emmanuelle Charpentier, PhD, has played a critical role in launching the field of CRISPR gene editing while moving between laboratories and countries in her search for a stable and independent research environment. While working at Umeå University, she collaborated with another CRISPR pioneer, Jennifer Doudna, PhD, a professor at the University of California, Berkeley, to show that an RNA-guided CRISPR enzyme, Cas9, could introduce double-stranded breaks in targeted DNA sequences. This work culminated in a classic paper that appeared in Science in 2012 and listed Charpentier and Doudna as co-corresponding authors.

Since then . . .

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