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June 30, 2008

Fraunhofer Institute Will Use Affymetrix Technology in Hepatotoxicity Studies

  • A team of researchers at the Fraunhofer Institute is using Affymetrix’ Whole Transcript  gene-expression technology to analyze the molecular mechanisms involved in the development of drug-induced liver injury. The ultimate goal of the project is to develop a diagnostic array that can detect signals of liver toxicity earlier and more accurately than traditional techniques.

    Affymetrix GeneChip® Exon and Gene Arrays allow for a more complete and accurate picture of overall gene expression  than traditional 3'-based expression arrays, according to the company, by enabling users to interrogate the entire length of the gene, not just the 3' end.