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August 01, 2007 (Vol. 27, No. 14)

Using AMDE Data to Cut Drug Toxicology Failures

Choosing In Vitro Models of the Relevant Species, Cell Type, and Metabolism

  • Getting human ADME/Tox data at the early stages of drug development could have substantial payoffs in terms of lowering lead candidates’ toxicology. Developing in vitro screening using human cells to counteract this was the focus of the recent “10th International Conference on Drug-Drug Interactions” held in Bellevue, WA. Making ...

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