Turning Cell Signaling against Cancer
Researchers Use Single-Molecule Assays, Splice-Switching Oligonucleotides, and Fusion Constructs
Virus Supply Vexes Gene Therapy Developers, CMOs
Some Contract Manufacturing Organizations Are Ramping Up Capacity in Preparation for a Boom in Viral Vector Demand
Viral Safety Copes with Complexity
Viral Clearance Calls for Bioprocess Engineers to Implement Control Strategies
Novel Viral Vectors for Gene Therapy
Synthetic Viral Vectors Show Promise for Mitigating Immune Response to Gene Therapy
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Tandem MS Zooms In on Glycosylation
Conventional Methods Are Inadequate When It Comes to Quantitative and Structural Analysis
- Characterization of the carbohydrate portion of glycoproteins in a high-throughput, cost-efficient manner presents myriad technological challenges. Unlike the linear peptide components of these molecules, carbohydrates can be complex, branched structures containing monomeric units that may link an oligosaccharide to a protein at more than one site. Furthermore, a ...
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