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May 15, 2014 (Vol. 34, No. 10)

Survey Kinase Activity from Kinomic Heights

  • Consistent with their central roles in cellular function and disease pathology, kinases are well represented in the human genome. In fact, more than 500 kinases have been identified. Kinases also reflect the complexity of signaling networks. It is well known, for example, that individual kinases can have stimulatory or ...

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