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February 01, 2009 (Vol. 29, No. 3)

Strategies to Overcome Blood-Brain Barrier

Complex Biology of CNS Diseases Continues to Hamper Development of Effective Drugs

  • Central nervous system (CNS) diseases are a major focus of the pharmaceutical industry, with CNS drugs representing some of its most successful products. These include Pfizer’s Zoloft, Eli Lilly’s Cymbalta, and Abilify from Bristol-Myers Squibb and Otsuka. Drug discovery and development researchers, however, have experienced difficulty developing ...

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