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January 15, 2011 (Vol. 31, No. 2)

RNAi Delivery Proves Vexing

Emerging Field Simultaneously Holds Both Promise and Problems

  • RNA interference (RNAi), an exciting yet evolving gene-silencing technology, holds great promise for drug discovery and as a novel therapeutic approach. But troubling doubts have recently emerged as to how quickly that promise will deliver. Perhaps ominously, in November, Roche terminated its multimillion-dollar RNAi therapeutics programs. One of ...

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