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March 01, 2009 (Vol. 29, No. 5)

Revitalizing Surface Plasmon Resonance

Resurgence Is Driven by SPR’s Aptitude for Fragment-Based Lead Discovery

  • Surface plasmon resonance, or SPR, is used to measure changes in molecular weight. Thus, it has  long been used to study protein-protein interactions by registering the association and dissociation of a ligand (prey) binding to an immobilized protein (bait).  SPR has recently been revitalized by its aptitude for ...

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