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April 15, 2009 (Vol. 29, No. 8)

Removing Impediments in Downstream Processing

Bottlenecks Are Not as Ubiquitous as Believed

  • For at least the last decade, protein purification has increasingly been viewed as a process bottleneck—not just for individual unit operations, but for the entire purification train. Current wisdom holds that production titers will continue to rise, and with them, the height and number of hurdles encountered downstream. While ...

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