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May 01, 2009 (Vol. 29, No. 9)

Ramping Up Effort for Improving Kinase Assays

Firms Use Myriad Strategies to Identify and Characterize Kinase Inhibitors

  • Protein kinases are at the forefront of drug discovery, representing the largest druggable class of compounds for the pharmaceutical industry with 518 kinases associated with approximately 400 diseases. There are many approaches to measure kinase activity in order to identify and characterize kinase inhibitors. The nature of kinases ...

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