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January 15, 2012 (Vol. 32, No. 2)

Protein Folding and Disease: The Path from Bench to Bedside

  • Cell biologists are exploring and exploiting protein-folding pathways as a source of drug targets for diseases involving disruption of protein homeostatis, or proteostasis. Such diseases affect proteome expression, protein function, and proteome maintenance. The “American Society for Cell Biology” (ASCB) annual meeting featured presentations that illustrated how managing ...

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