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November 01, 2013 (Vol. 33, No. 19)

PCR @ 30: From Whence It Sprang

  • In the summer of 1984, Henry Erlich, Glenn Horn, Randy Saiki, and myself were working on developing a DNA test for sickle cell anemia (SCA) at Cetus Corp. SCA is an autosomal dominant disease caused by a single base mutation in the β-globin subunit of the hemoglobin gene. ...

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