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February 01, 2012 (Vol. 32, No. 3)

Measuring and Characterizing Protein Aggregates

  • Starting with the first protein drug, insulin, in 1982, recombinant proteins have played a vital and growing role in the treatment of human disease.Yet inherent to the production of protein drugs is the possibility of aggregation, which may increase the risk of an immunogenic response to the dosed drug. ...

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