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November 15, 2011 (Vol. 31, No. 20)

Improving Classic Antibody Engineering

Diverse Methodologies and Fresh Insights Turn a Good Technique into an Even Better One

  • Antibody engineering holds the potential for creating antibodies with multiple specificities, greater affinity for their targets, and fewer side effects. Among these approaches, more-or-less traditional protein engineering remains a topic of intense interest. Zymeworks whose trademarked tagline is “Building Better Biologics™,” describes its technology as “structure-guided design.” Those ...

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