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April 15, 2008 (Vol. 28, No. 8)

HTS Carving Out Hit-to-Lead Position

Researchers Are Coupling this Technology with Other Methodologies to Enable Better Screening

  • Pressure to discover more hits and develop more blockbuster drugs with less time and expense spent on target screening continues to spur companies to invest in high-throughput technologies earlier in the drug discovery process. In addition, there is a trend toward combining cell biology, imaging, and in vivo experimentation skills. ...

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