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March 15, 2015 (Vol. 35, No. 6)

Glycosylation: The Key to Quality

To Generate Therapeutic Glycoproteins of Consistent Quality, Bioprocessors Must Control for an Abundance of Variables

  • Glycosylation of therapeutic proteins is nearly always mentioned within the context of quality and consistency. Critical quality attributes (CQAs) are affected by multiple factors, including clone selection, culture and purification conditions, formulation, and storage conditions. For Elizabeth Dodson, Ph.D., an R&D manager in the advanced bioprocessing unit of ...

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