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April 15, 2017 (Vol. 37, No. 8)

Finding Targets in Cancer’s Metabolic Quirks

To Head Off Cancer at the Pass, Take Directions from Pathway Analysis

  • Almost 100 years ago, German biochemist Otto Heinrich Warburg noticed that cancer cells tend to have a high rate of glycolysis compared to normal tissues. This phenomenon, which occurs in cancer cells along with increased glucose uptake and fermentation of glucose to lactate, is known as the Warburg effect. ...

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