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September 15, 2011 (Vol. 31, No. 16)

Expression System Gains Lead to High Protein Yields

Current CHO Cell, <em>E.coli</em>, and Yeast Platforms Creating a Healthy Dose of Idle Capacity

  • Continued improvements in recombinant protein expression yields have helped ease production capacity constraints, leading to an apparently healthy and manageable increase in idle capacity. According to BioPlan Associate’s 8th annual survey of biopharmaceutical manufacturers, the overall average yield reported for commercial monoclonal antibody this year was 2.18 g/L—up from ...

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