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August 01, 2007 (Vol. 27, No. 14)

Effective Optimization: Fight or Flight?

Integration of Tools and Other Advances Is Making Process More Feasible and Successful

  • Cambridge Healthtech Institute’s sixth annual “World Pharmaceutical Congress” focused on lead optimization with the goal of increasing the efficiency of the hit-to-lead-to-drug candidate process. A roundtable discussion moderated by Christopher B. Cooper, Ph.D., associate director of early discovery chemistry at Bristol-Myers Squibb (www.bms.com), asked the question “Lead Optimization vs. ...

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