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August 01, 2013 (Vol. 33, No. 14)

Diving Deep with Array CGH

  • While single-nucleotide polymorphisms were an initial focus, the subsequent discovery of copy-number variation unveiled a new dimension of genomic diversity, and made apparent the need to develop more refined technologies to capture chromosomal rearrangements. Comparative genomic hybridization (CGH) provided the opportunity to detect chromosomal imbalances in a high-throughput ...

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