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July 01, 2009 (Vol. 29, No. 13)

Creating Therapies via the RNAi Route

New Transfection Systems Tackle Delivery Issues and Off-Target Effects

  • Will RNAi-based therapeutics provide the next class of blockbuster drugs? If pharma’s acquisition spree of companies with relevant technologies proves predictive, then all bets are on. In 2001, siRNA duplexes were hailed as new tools for studying gene function in mammalian cells, and it was predicted that they eventually ...

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