Improvements to Gene Therapy Clinical Trial Design Benefit Hemophilia Patients
Gene Therapy Allows Hemophilia Patients to Give Up Medication, Avoid Bleeds; but More Improvements Are Needed
Turning Cell Signaling against Cancer
Researchers Use Single-Molecule Assays, Splice-Switching Oligonucleotides, and Fusion Constructs
To Gild the Microbe Is Anything but Wasteful
Synthetic Biology Is Enabling Optimization that Is Iterative—and Remunerative
Novel Viral Vectors for Gene Therapy
Synthetic Viral Vectors Show Promise for Mitigating Immune Response to Gene Therapy
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Copy Number Variation Probes Inform Diverse Applications
Better Methods to Analyze and Organize DNA Fragments Are Emerging
- The evolution of the MUC7 gene, which encodes a saliva protein, was studied by scientists at the University at Buffalo. To capture the gene’s proline-, threonine-, and serine-rich tandem repeat copy number variations (CNVs), the scientists analyzed more than 2,500 genomes. This extensive work revealed that MUC7 subexonic CNVs ...
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