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October 01, 2013 (Vol. 33, No. 17)

CNV Strategies Get a Rethink

  • The discovery that 20,000–24,000 protein-encoding genes exist in the haploid human genome (a key finding of the Human Genome Project) fueled initiatives to map gene interactions and characterize the genetic circuitry in cells. Radiation hybrid mapping, a strategy in which high-dose X-rays randomly introduce chromosomal breaks that shatter ...

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